Methods

1.      First Generation of Short Oligonucleotide Sequencing Assay (SOSA):

Fiala, K.A. and Suo, Z.* (2007) Sloppy Bypass of an Abasic Lesion Catalyzed by a Y-family DNA Polymerase.  J. Biol. Chem.  282, 8199-8206. ( pdf ) ( SI ) [ Press Release ]

2.      Second Generation of Short Oligonucleotide Sequencing Assay (SOSA):

Taggart, D.J., Camerlengo, T.L., Harrison, J.K., Sherrer, S.M., Kshetry, A.K., Taylor, J., Huang, K., Suo, Z.* (2013) A High-Throughput and Quantitative Method to Assess the Mutagenic Potential of Translesion DNA,  Nucleic Acids Research . Volume 41, Issue 8, Pages e96.  [Online Access ]

(Note: If you need the NGS Position Counter program for analyzing HT-SOSA data, please contact Dr. Zucai Suo)

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