VIRAL VECTOR & GENE EDITING CORE
Whether you are an experienced researcher or just getting started with gene delivery and genome engineering, the Florida Institute for Pediatric Rare Diseases (IPRD) Viral Vector and Gene Editing Core (VVGEC) service is here to help. We offer expert support, custom services, and a friendly, collaborative approach to meet your scientific goals.
The IPRD Viral Vector and Gene Editing Core is a full-service facility specializing in the design, development, and production of viral vectors and gene editing tools. We support research projects of all types and sizes, and our services are available to academic, clinical, and industry partners.
We offer everything from small pilot batches to large-scale vector production, along with consultation and project design support every step of the way.
Core Services Overview
Here are some of the ways we can support your research:
Viral Vector Services
- Design, construction, and cloning of plasmids for gene delivery
- Ready-to-use vector backbones for your gene of interest
- Production of lentivirus, AAV, retrovirus, and adenovirus vectors
- Support for in vitro and in vivo applications
- Flexible production scales: small, mid, or large batches
- Naïve and reporter constructs in both AAV and lentiviral formats
- Robust quality control, including plasmid sequencing and safety testing.
Personalized Project Support
Our team works closely with investigators to design and deliver custom solutions. We provide one-on-one consultations to:
- Recommend appropriate viral vector platforms and gene editing tools
- Select optimal serotypes or pseudotypes for your target tissues or cells
- Help integrate CRISPR tools with transgenic animal models
- Support every step from concept to implementation
GENE EDITING SERVICES
- Access to more than 5000 gene editing systems from leaders in the field
- Inducible and constitutive editors
- Consultation on vector selection and application design
Protein and Antibody Engineering
- Custom design of antibodies, enzymes, and protein switches
- Engineering of proteins with novel binding or signaling capabilities
- Support from early-stage discovery through stable cell line development
Optogenetics
- Access to more than 500 optogenetic vectors from leaders in the field (comprehensive collections from Karl Deisseroth, Bryan Roth, Ed Boyden labs and others)
- Tools to control cell activity with light in complex tissues
- Consultation on vector selection and application design
Why Choose Us? We Offer: