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College of Medicine Spotlight: The Cutting Edge
Article Recommendation in F1000Prime
Our recent publication in JACS , “Functional Insights Revealed by the Kinetic Mechanism of CRISPR/Cas9” has been recommended in F1000Prime .
Article Recommendation in F1000Prime
Our recent publication in Nature , “Dynamic basis for dG•dT misincorporation via tautomerization and ionization," has been recommended in F1000Prime as being of special significance in its field.
Press Release for recent Cas9 publications in JACS
The Suo lab has recently published two articles in the Journal of the American Chemical Society detailing the kinetic mechanism of CRISPR/Cas9 as well as identifying and characterizing a novel activity of Cas9. [ Kinetic Mechanism Publication ][ New Activity Publication ] The publications have been featured on the OSU Chemistry Department website. [ Press Release ]
Article Commentary in Nature
Myron Goodman, a respected researcher in the field, has written a commentary in Nature on our recent publication in Nature , “Dynamic basis for dG•dT misincorporation via tautomerization and ionization." [ Commentary ]
Nature Article Press Releases
Our recent publication in Nature , “Dynamic basis for dG•dT misincorporation via tautomerization and ionization," has been featured on the Ohio State University and Duke University Chemistry Department websites. [ OSU Press Release ] [ Duke Press Release ]
Article Commentary in Cell
Samuel F. Bakhoum and Daniel A. Landau have written a commentary on our recent publication in Cell , “Comprehensive analysis of hypermutation in human cancer”. [ Commentary ]
Publication becomes No. 1 Most Downloaded in the Past Year
Our 2017 publication in Aids Research and Human Retroviruses , “Long-term survival of AIDS patients treated with only traditional Chinese medicine," has become the No. 1 most downloaded publication of that journal in the past 12 months (as of December 2017).
Article Featured in an Editorial Commentary
Our recent 2017 publication in Aids Research and Human Retroviruses , “Long-term survival of AIDS patients treated with only traditional Chinese medicine” has been featured in an editorial written in the same issue of Aids Research and Human Retroviruses . [ Online Access ]
Article Featured on Med123
Our recent 2017 publication in Aids Research and Human Retroviruses , “Long-term survival of AIDS patients treated with only traditional Chinese medicine” has been featured in a news report on Med123 (in Chinese). [ Online Access ]
Article Featured on MedicalXpress
Our recent 2017 publication in Aids Research and Human Retroviruses , “Long-term survival of AIDS patients treated with only traditional Chinese medicine” has been featured in a press release on MedicalXpress . [ Online Access ]
Article Featured on EurekAlert!
Our recent 2017 publication in Aids Research and Human Retroviruses , “Long-term survival of AIDS patients treated with only traditional Chinese medicine” has been featured in a press release on EurekAlert! , an online global science news outlet sponsored by the American Association for the Advancement of Science. [ Online Access ]
Article Featured in APS Science Highlight
Our 2015 publication in JACS , “Viewing Human DNA Polymerase β Faithfully and Unfaithfully Bypass an Oxidative Lesion by Time-Dependent Crystallography,” has been featured in the April 26th, 2016 edition of APS Science Highlight . [ Online Access ]
Article Recommended in F1000Prime
Our recent publication in JACS , “Mechanistic Basis for the Bypass of a Bulky DNA Adduct Catalyzed by a Y-Family DNA Polymerase,” has been recommended in F1000Prime as being of special significance in its field.
Article Recommended in F1000Prime
Our recent publication in JACS , “Viewing Human DNA Polymerase β Faithfully and Unfaithfully Bypass an Oxidative Lesion by Time-Dependent Crystallography,” has been recommended in F1000Prime as being of special significance in its field.
Article chosen to be featured on the home page of the journal PLOS Computational Biology
The 2014 article “Dynamic conformational change regulates the protein-DNA recognition: An investigation on binding of a Y-family polymerase to its target DNA” was chosen to be featured on the home page of PLOS Computational Biology in Semptember, 2014.
Chemical & Engineering News Article about Nucleoside Analogs as Potent Anticancer Drugs
Our lab's work was referenced in Chemical & Engineering News . Click here to read the article.
Dr. Suo Elected to the AAAS
Dr. Suo was elected as a Fellow for the American Association for the Advancement of Science for distinguished contributions to the field of nucleic acid enzymology, particularly for pre-steady state kinetic and protein conformational dynamic studies of DNA polymerases. Read about it here .
Article chosen to be featured on the home page of the journal Biochemistry
The review article “Unlocking the Sugar ‘Steric Gate’ of DNA Polymerases” has been selected to be featured on Biochemsitry’s home page for the February 22, 2011 issue.
Click here to read the article.
Publication Featured on MDLinx
The publication “ Pre-steady state kinetic analysis of the incorporation of anti-HIV nucleotide analogs catalyzed by human X- and Y-family DNA polymerases ” has beenhighlighted by MDLinx, an internet-based service that offers physicians and other healthcare professionals a quick means of staying current with academic literature.
Click here to read the article.
Scientists Are First to Observe the Global Motions of an Enzyme Copying DNA
Click here to read the article which covers the “ Global Conformational Dynamics of a Y-family DNA Polymerase during Catalysis ” publication. This publication has been evaluated at the Faculty of 1000 Biology website .
Graduate Student Named an NSF Fellow
Lindsay Pack was named an NSF, Click here to see the announcement from OSU.
Protein Averts Cell Death
Click here to view the extensive list of websites covering the “ Mechanism of Abasic Lesion Bypass Catalyzed by a Y-Family DNA Polymerase ” and “ Sloppy Bypass of an Abasic Lesion Catalyzed by a Y-Family DNA Polymerase as Revealed by a Novel Cell-Based Short Oligonucleotide Sequencing Assay ” publications. These recent discoveries may help shed some light on how a cell deals with DNA damage that may lead to cancer.
Article Discussed in Medical News Today
Click here to read the article which covers the “ Up-regulation of the fidelity of human DNA polymerase lambda by its non-enzymatic proline-rich domain ” publication, titled "Repair Protein Kept Accurate by Unusual Mechanism."